The difference between Futile and Vain
When used as adjectives, futile means incapable of producing results, whereas vain means overly proud of oneself, especially concerning appearance.
check bellow for the other definitions of Futile and Vain
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Futile as an adjective:
Incapable of producing results; doomed not to be successful; not worth attempting.
Examples:
"synonyms: useless"
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Vain as an adjective:
Overly proud of oneself, especially concerning appearance; having a high opinion of one's own accomplishments with slight reason.
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Vain as an adjective:
Having no real substance, value, or importance; empty; void; worthless; unsatisfying.
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Vain as an adjective:
Effecting no purpose; pointless, futile.
Examples:
"'vain toil;  a vain attempt"
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Vain as an adjective:
Showy; ostentatious.