The difference between Screw and Stuff
When used as nouns, screw means a simple machine, a helical inclined plane, whereas stuff means miscellaneous items.
When used as verbs, screw means to connect or assemble pieces using a screw, whereas stuff means to fill by crowding something into.
check bellow for the other definitions of Screw and Stuff
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Screw as a noun (nautical):
A device that has a helical function. A simple machine, a helical inclined plane. A (usually) metal fastener consisting of a shank partially or completely threaded shank, sometimes with a threaded point, and a head used to both hold the top material and to drive the screw either directly into a soft material or into a prepared hole. A ship's propeller. An Archimedes screw. A steam vessel propelled by a screw instead of wheels.
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Screw as a noun (derogatory):
A prison guard.
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Screw as a noun (derogatory):
An extortioner; a sharp bargainer; a skinflint.
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Screw as a noun (US, slang, dated):
An instructor who examines with great or unnecessary severity; also, a searching or strict examination of a student by an instructor.
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Screw as a noun (vulgar, slang):
Sexual intercourse; the act of screwing.
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Screw as a noun (vulgar, slang):
A casual sexual partner.
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Screw as a noun (slang):
Salary, wages.
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Screw as a noun (billiards):
Backspin.
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Screw as a noun (slang):
A small packet of tobacco.
Examples:
"rfquotek Mayhew"
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Screw as a noun (dated):
An old, worn-out, unsound and worthless horse.
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Screw as a noun (math):
A straight line in space with which a definite linear magnitude termed the pitch is associated. It is used to express the displacement of a rigid body, which may always be made to consist of a rotation about an axis combined with a translation parallel to that axis.
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Screw as a noun:
An amphipod crustacean.
Examples:
"the skeleton screw (Caprella);  the sand screw'"
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Screw as a verb (transitive):
To connect or assemble pieces using a screw.
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Screw as a verb (transitive, vulgar, slang):
To have sexual intercourse with.
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Screw as a verb (transitive, slang):
To cheat someone or ruin their chances in a game or other situation. Sometimes used in the form "screw over".
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Screw as a verb (transitive):
To apply pressure on; to put the screws on.
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Screw as a verb:
To practice extortion upon; to oppress by unreasonable or extortionate exactions.
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Screw as a verb (transitive):
To contort.
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Screw as a verb (soccer, transitive):
To miskick (a ball) by hitting it with the wrong part of the foot.
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Screw as a verb (billiard, snooker, pool):
To screw back.
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Screw as a verb (US, slang, dated):
To examine (a student) rigidly; to subject to a severe examination.
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Stuff as a noun:
Miscellaneous items; things; (with possessive) personal effects.
Examples:
"What is all that stuff on your bedroom floor?  nowrap He didn't want his pockets to bulge so he was walking around with all his stuff in his hands."
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Stuff as a noun (slang, informal):
Things; trivial details.
Examples:
"I had to do some stuff."
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Stuff as a noun:
The tangible substance that goes into the makeup of a physical object.
Examples:
"synonyms: matter Thesaurus:substance"
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Stuff as a noun:
A material for making clothing; any woven textile, but especially a woollen fabric.
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Stuff as a noun:
Abstract substance or character.
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Stuff as a noun (informal):
Examples:
"synonyms: doodad thingamabob Thesaurus:thingy"
"Can I have some of that stuff on my ice-cream sundae?"
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Stuff as a noun (slang):
Narcotic drugs, especially heroin.
Examples:
"synonyms: dope gear Thesaurus:recreational drug"
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Stuff as a noun (obsolete, uncountable):
Furniture; goods; domestic vessels or utensils.
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Stuff as a noun (obsolete):
A medicine or mixture; a potion.
Examples:
"rfquotek Shakespeare"
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Stuff as a noun (obsolete):
Refuse or worthless matter; hence, also, foolish or irrational language; nonsense; trash.
Examples:
"synonyms: garbage rubbish Thesaurus:trash"
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Stuff as a noun (nautical):
A melted mass of turpentine, tallow, etc., with which the masts, sides, and bottom of a ship are smeared for lubrication.
Examples:
"rfquotek Ham. Nav. Encyc"
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Stuff as a noun:
Paper stock ground ready for use. When partly ground, it is called half stuff.
Examples:
"rfquotek Knight"
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Stuff as a verb (transitive):
To fill by crowding something into; to cram with something; to load to excess.
Examples:
"She stuffed the turkey for Thanksgiving using her secret stuffing recipe."
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Stuff as a verb (transitive):
To fill a space with (something) in a compressed manner.
Examples:
"He stuffed his clothes into the closet and shut the door."
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Stuff as a verb (transitive):
To load goods into a container for transport.
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Stuff as a verb (transitive, used in the passive):
To sate.
Examples:
"I’m stuffed after having eaten all that turkey, mashed potatoes and delicious stuffing."
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Stuff as a verb (transitive, British, Australia, New Zealand):
To break.
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Stuff as a verb (transitive, vulgar, British, Australia, New Zealand):
To sexually penetrate.
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Stuff as a verb (transitive):
To cut off another competitor in a race by disturbing his projected and committed racing line (trajectory) by an abrupt manoeuvre.
Examples:
"I got stuffed by that guy on the supermoto going into that turn, almost causing us to crash. "
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Stuff as a verb:
To preserve a dead bird or other animal by filling its skin.
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Stuff as a verb (transitive):
To obstruct, as any of the organs; to affect with some obstruction in the organs of sense or respiration.
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Stuff as a verb (transitive):
To form or fashion by packing with the necessary material.
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Stuff as a verb (transitive, dated):
To crowd with facts; to cram the mind of; sometimes, to crowd or fill with false or idle tales or fancies.
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Stuff as a verb (transitive, computing):
To compress (a file or files) in the format, to be unstuffed later.
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Stuff as a verb (pronominal):
To eat, especially in a hearty or greedy manner.