The difference between Milquetoast and Sissy
When used as nouns, milquetoast means a person of meek or timid disposition, whereas sissy means an effeminate boy or man.
When used as adjectives, milquetoast means meek, timid, whereas sissy means effeminate.
Sissy is also verb with the meaning: to urinate.
check bellow for the other definitions of Milquetoast and Sissy
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Milquetoast as an adjective:
Meek, timid.
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Milquetoast as a noun (pejorative):
A person of meek or timid disposition.
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Sissy as a noun (pejorative, colloquial):
An effeminate boy or man.
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Sissy as a noun (pejorative, colloquial):
A timid, unassertive or cowardly person.
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Sissy as a noun (BDSM):
A male crossdresser who adopts feminine behaviours.
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Sissy as a noun (colloquial):
Sister.
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Sissy as an adjective (pejorative):
Effeminate.
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Sissy as an adjective (pejorative):
Cowardly.
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Sissy as a noun (childish, colloquial):
Urination; urine.
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Sissy as a verb (childish, colloquial):
To urinate.