The difference between In the main and Mainly
In the main is also phrase with the meaning: principally.
Mainly is also adverb with the meaning: forcefully, vigorously.
check bellow for the other definitions of In the main and Mainly
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Mainly as an adverb (obsolete):
Forcefully, vigorously.
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Mainly as an adverb (obsolete):
Of the production of a sound: loudly, powerfully.
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Mainly as an adverb (obsolete):
To a great degree; very much.
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Mainly as an adverb:
Chiefly; for the most part.