The difference between Diastereoisomer and Enantiomer
When used as nouns, diastereoisomer means a stereoisomer having multiple chiral centres, whereas enantiomer means one of a pair of stereoisomers that is the mirror image of the other, but may not be superimposed on this other stereoisomer. almost always, a pair of enantiomers contain at least one chiral center, and a sample of either enantiomer will be optically active.
check bellow for the other definitions of Diastereoisomer and Enantiomer
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Diastereoisomer as a noun (chemistry):
A stereoisomer having multiple chiral centres; a diastereoisomer cannot normally be superimposed on the mirror image of another.
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Enantiomer as a noun (chemistry):
One of a pair of stereoisomers that is the mirror image of the other, but may not be superimposed on this other stereoisomer. Almost always, a pair of enantiomers contain at least one chiral center, and a sample of either enantiomer will be optically active.