The difference between Guidette and Guido
When used as nouns, guidette means italian-american female, whereas guido means italian-american male.
check bellow for the other definitions of Guidette and Guido
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Guidette as a noun (slang, US, ethnic slur):
Italian-American female; an American female of Italian descent.
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Guido as a noun (slang, US, ethnic slur):
Italian-American male; an American male of Italian extraction as a member of the working-class.